Published Paper Details:

Abstract: Artemisia nilagirica is a wild perennial hardy plant belongs to Asteraceae family. It has important medicinal values to cure human sickness. In the present study, aqueous, methanol and diethyl ether extract of Artemisia nilagirica stem and root was extracted. The phytochemical screening, antioxidant, antibacterial and anticoagulant activity were determined. In phytochemical screening the stem and root of Artemisia nilagirica proved the presence of rich bioactive compounds in all the three solvent extracts. The antioxidant potential was determined using DPPH with vitamin C as standard, vitamin C estimation to determine the non enzymic antioxidant potential and reducing power assay which all gave values close to standard ascorbic acid. Antibacterial activity was performed using disc diffusion method against Staphylococcus aureus, Klebsiella pneumonia and Enterococcus faecalis in the presence of stem and root extract of all 3 solvents. It was found that diethyl ether extract of stem showed maximum activity against Enterococcus faecalis at the range of 7mm. Anticoagulant activity was conducted which exhibited that the aqueous root showed the maximum coagulation time as 30mins:10sec by prothrombin test compared to all the other samples indicating the stem and root of A.nilagirica is a potential candidate rich in phytochemicals, antioxidant, antibacterial and anticoagulant properties.