Published Paper Details:

Medicinal plants and their endophytes are potent resources for discovery of novel bioactive metabolites. The endophytic fungi from plants were an important source for the production of various secondary metabolites, bioactive compounds which are useful in pharmacology, agriculture and in industries. Endophytic fungi are a group of fungi that colonize living and internal tissues of plants without causing any immediate, over negative effects The capability of medicinal plant endophytic fungi for the production of bioactive secondary metabolites was evaluated under in vitro conditions. In the present investigation, the diversity of endophytic fungi was studied associated with medicinally important plant Aloe vera. A total of 50 fungal species from Aloe vera were isolated and categorized under eight species based on the morphology of the fungal culture and characteristics of the spores. Secondary metabolites produced from isolated endophytic fungi was subjected to investigation and challenged for their antibacterial activity. Among the eight endophytic culture isolated , all the cultures were subjected to medium optimization to produce host marker compounds . The crude extract produced was profiled using thin layer chromatography and found that Aloe vera host compounds were also found secreted by the isolated endophytic fungus . Thus it gives an interesting note that medicinally important Aloevera compounds shall also obtained from the endophytic cultures isolated from aloevera , with out exploiting the Aloe vera for its compounds