Published Paper Details:

Specific pathogens have been implicated in acute and chronic gastrointestinal disease due to compositional changes in intestinal microbiota, and lack of immunity leads puppies and adult dogs susceptible to pathogens causing severe gastroenteritis. Gastroenteritis is an inflammation of stomach and intestine and rupture of epithelial cells leading severe bloody diarrhea. The most significant opportunistic pathogens of gastrointestinal tract are parasites, protozoans, viral agents like Canine Parvovirus, Canine Coronavirus, Canine Distemper virus, Rota virus with bacterial co-infection by Salmonella spp, E. coli, Clostridium, Campylobacter that causes severe gastroenteritis in dogs. Canine parvovirus 2 (CPV-2) infection is highly contagious viral disease in dogs, which is prevalent all over the world and they are highly fatal. Second most contagious intestinal disease in dogs is canine coronavirus infection. The main mode of transmission is by ingestion of infected fecal contaminated material. Salmonellosis caused by Salmonella typhimurium is the most common infectious disease in dogs transmitted by fecal matter contamination in foods such as raw meat, chicken, and also occurs more frequently in latent forms. They also cause secondary infection with viral gastroenteritis.