Published Paper Details:

Background: Adverse Drug Reactions are the recognized hazards of drug therapy and they can occur with any class of drugs. The main aim of this study was to detect, assess, monitor and prevention of adverse drug reactions in inpatients of a tertiary care hospital. Methods and Material: It was a prospective observational study on adverse drug reactions was carried out among inpatients who were between 18-85 years in the tertiary care hospital. A total of 200 prescriptions of patients were included in study. The collected data was sorted and analyzed on the basis of severity, age and gender. Results: A total of 90 ADRs were reported during the study period with male predominance (52%) and geriatric age group. More number of ADRs was from General Medicine and Neurology departments in which the most affected organ system were the Skin (26%) and the GIT (25.5%). The severity assessment revealed that most of them were severe (51%) followed by moderate and mild reactions. Of the reported reactions 33% were definitely preventable and casuality assessment was done which showed that 56% were definite, probable (26%), possible (8%). Conclusion: The study concluded that adverse drug reactions to drugs are common and some of them resulted in increased healthcare cost due to the need of some interventions and increased length of hospital stay. The health system should promote the spontaneous reporting of Adverse Drug Reactions to drugs, proper documentation and periodic reporting to regional pharmacovigilance centers to ensure drug safety.