Published Paper Details:

Background: Burns are a global public health problem caused by the high rate of burn mortality and morbidity. Based on the medical records of RSUP Haji Adam Malik Medan, there were 353 cases of burns in 2011-2014, the most common cause was flame burn injury. ). The optimal concentration of topical vitamin C which has a biologically significant effect with a concentration greater than 8% and a concentration greater than 20% does not have a significant biological effect. Objective: This study examined the effect of topical vitamin C administration on mid-dermal burns on increased collagen deposition. Methods: This study is an experimental study. The research design used in this study is a simple experimental design (Post Test Only Control Group Design). A total of 40 samples were analyzed on the 14th day after burns induction consisting of 2 groups, namely 20 samples from the control group and 20 samples from the experimental group (vitamin C). Results: In the analysis of collagen scores, most cases in the experimental group had moderate and intense collagen scores with 8 samples (40%) of each case. Whereas in the control group, most cases had a focal collagen score (55%). Using the Mann Whitney test, there was a significant difference in collagen scores between the control group and the experimental group (p = 0.001). Conclusion: Vitamin C is effective in the healing process of burns. Topical use of vitamin C can be an option for patients who have large burn areas.