Published Paper Details:

Skin delivery is one of the most frequently method used for drug application. But due to rough and tough nature of skin there is always been a search of a carrier that easily penetrate the uppermost layer of skin hence provide significant therapeutic effect. In recent years researchers focus on potential of nanocarriers as drug delivery system in various routes of dug administration. Liposome, niosomes, polymeric nanocarriers, carbon nanocarriers, SLN, NLC are some of the recently used carriers. The safety and toxicity of some nanocarriers is always a matter of conflict so limits their use as drug carriers. NLCs are second generation lipid carriers and due to its structural integration has wide opportunity in topical drug delivery. In this article we review the utilization of NLC and the work done on recent advancement in this field. Review mainly focus on the delivery of NLC in various topical diseases and applicability as drug carrier.