Published Paper Details:

Periodontitis is a multifactorial disease of the supporting tissues of the teeth. Bone loss and attachment loss occur by the untreated periodontitis. Periodontal tissue regeneration has always been a dare for the periodontist because of its structural intricacy. However, with tissue engineering as a rising multidisciplinary branch, this aim has partially been fulfilled. Regeneration is reconstruction of both hard and soft tissues in structure and function. Various treatment modalities i.e. bone grafts and substitutes, guided tissue regeneration (GTR) membranes and growth factors (PGFs) are used for periodontal regeneration. Platelet concentrates are abundant source for growth factors. Platelet concentrates are prepared from the patient�s own blood throughout that the activated platelets are become close among a fibrin matrix scaffold and release growth factors and cytokines played key role in tissue regeneration; including cell proliferation and differentiation, extracellular matrix synthesis, chemotaxis and angiogenesis. This review highlights various types of platelet concentrates, and there clinical applications within the treatment of periodontal diseases.