Published Paper Details:

Now a days Rheumatic Arthritis increasing in population and for the treatment of Rheumatic Arthritis patient take medicine whole life. For treatment we use various type of NSAID but prolong use of those drug shows many side effects like ulcerative colitis, IBD, CD, Stomach Ulcer, Liver Cirrhosis and many more which occurred with type of drug and duration of treatment. Many Present study describes the Etodolac used in the treatment of Rheumatic Arthritis, but prolong use of Etodolac shows some saviour side effect on human body. Curcumin also used in the treatment of Rheumatic Arthritis. The purpose of study is to develop and formulate such formulation which minimize side effect of Etodolac and treat Rheumatic Arthritis effectively for long duration of treatment. For avoid acid degradation of curcumin we prepare enteric coated tablet which release drug directly into intestine. From the above evaluations of all batches it is concluded that F4 batch was the optimized batch. F4 batch was found stable for 3 months (400C�20C, RH 75%�5%).