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ABSTRACT Background: breast engorgement is occurs due to expansion and pressure exerted by the synthesis and storage of breast milk. Breast feeding is decreased many problems such as infections, breast engorgement and other medical problems. Methods: A Quantitative pre-experimental study was conducted to assess the knowledge regarding prevention of breast engorgement among postnatal mothers. Thirty postnatal mothers were selected by Non probability convenience sampling technique. Data was collected by using structured questionnaire (30) to assess the knowledge of postnatal mother. Result: Result showed that pretest mean score of knowledge regarding prevention of breast engorgement was 10.4 and post-test mean score was 21.4. It Shows that there was significant difference in the mean pre-test knowledge score and mean post-test knowledge score of postnatal mothers on prevention of breast engorgement as measured by �t� test (24.2) which was significant at 0.05 level of significance. There was not significant relationship between selected demographic variables with knowledge of postnatal mothers. Conclusion: The study concluded that structured teaching programme was effective which improve the knowledge of postnatal mothers.