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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
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Paper Title
A REVIEW ON MECHANISM , MANAGEMENT AND FUTURE PROSPECTS FOR THE DRUG DRUG INTERACTION
Authors
Vaibhav Haramkar, Shrikrushna Subhash unhale , Baliram Bhutekar, Sujata Salve , Vaishnavi Patil, Prof Pavan Folane, Prof . Dr. K .R. Biyani
Keywords
DDI � drug drug interactions , Drugs , absorption , adverse effects , Cytochrome P450 , enzymes
Abstract
In the future , many drug- drug interactions ( DDI ) scenarios may be mapped using computer simulations but for now , laboratories are working to keep up with ever � shifting regulations including those for in vitro metabolism and transporter mediate DDI studies .
A change in a drugs effect on the body when the drug is taken together with a second drug . A DDI can delay decrease or enhance absorption of either drug .this can decrease or increase the action of either or both drugs or cause adverse effects.
One example of this type of DDI is where the therapeutic protein changes the level of cytochrome P450 ( cyp enzyme ) . In the liver , where this Change In the cyp enzyme has an effect on the coadministered small molecule drug .
IJCRT's Publication Details
Unique Identification Number - IJCRT2004095
Paper ID - 193180
Page Number(s) - 755-766
Pubished in - Volume 8 | Issue 4 | April 2020
DOI (Digital Object Identifier) -
Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Cite this article
Vaibhav Haramkar, Shrikrushna Subhash unhale , Baliram Bhutekar, Sujata Salve , Vaishnavi Patil, Prof Pavan Folane, Prof . Dr. K .R. Biyani, "A REVIEW ON MECHANISM , MANAGEMENT AND FUTURE PROSPECTS FOR THE DRUG DRUG INTERACTION ", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.8, Issue 4, pp.755-766, April 2020, Available at :http://www.ijcrt.org/papers/IJCRT2004095.pdf
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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