Published Paper Details:

A Rapid and sensitive U.V. spectrophotometric method for the determination of Metformin Hydrochloride Hydrochloride and Rosuvastatine calcium calcium in the pharmaceutical synthetic mixture was developed. The UV spectroscopy method was performed at 232.6 nm for Metformin Hydrochloride Hydrochloride and 240.4 nm for Rosuvastatin and samples were prepared by using water as solvent. The linearity range for Metformin Hydrochloride is 5-25 ?g/ml and for Rosuvastatine calcium is 0.4-2.0 ?g/ml. Regression Coefficient For Metformin Hydrochloride and Rosuvastatine calcium is 0.999 and 0.998 respectively. The LOD and LOQ for Metformin Hydrochloride e was found to be 0.264 ?g/ml and 0.80 ?g/ml respectively. The LOD and LOQ for Rosuvastatine calcium was found to be 0.1143 ?g/ml and 0.3464 ?g/ml respectively. The proposed methods were simple, rapid, precise, accurate and sensitive can be used for routine of the quality control in pharmaceuticals.