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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
Call For Paper - Volume 12 | Issue 6 | Month- June 2024
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Paper Title
IN-SILICO DRUG DISCOVERY FOR COVID19 BY TARGETING SPIKE GLYCOPROTEIN OF SARS COV - 2 (WUHAN CORONA VIRUS 2019 OUTBREAK) AGAINST THE DOCKING ANALYSIS WITH STRUCTURE PREDICTED HUMAN �ACE2-FC REGION OF IGG1� FUSION PROTEIN AS A PROTEIN BASED DRUG.
Authors
PANDIYA MUTHU KUMARAN, KALIDAS VIJAYAKUMAR
Keywords
SARS CoV 2,Novel Corona Virus ,ACE2-FC REGION IgG1,COVID19,INSILICO DRUG DISCOVERY.
Abstract
Abstract:The globe was frightened with a newly isolated virus named as sars cov 2 formally called as novel corona virus 2019.This work is predicting a protein based drug for sars cov 2.A virus was outbreaks at wuhan city of china on December 2019.The RNA sequence of that virsus was published in NCBI.(NCBI Ref Sequence:NC_045512.2)We collected the serface glycoprotein sequences from NCBI and genbank and predicted the protein structure with swiss model and phyre 2 protein structure prediction tools.The predicted spike glycoprotein was have a docking function with the human ACE2 receptor.We predicted the 3D structure of ACE2- FC region of IgG1 fusion protein and docked with virus spike glycoprotein and found a good docking potential of fusion protein with Sars Cov 2.ACE2- FC region of IgG1 will be use as a protein drug against
SarsCoV 2.
IJCRT's Publication Details
Unique Identification Number - IJCRT2002193
Paper ID - 192151
Page Number(s) - 1667-1675
Pubished in - Volume 8 | Issue 2 | February 2020
DOI (Digital Object Identifier) - http://doi.one/10.1729/Journal.23206
Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Cite this article
PANDIYA MUTHU KUMARAN, KALIDAS VIJAYAKUMAR, "IN-SILICO DRUG DISCOVERY FOR COVID19 BY TARGETING SPIKE GLYCOPROTEIN OF SARS COV - 2 (WUHAN CORONA VIRUS 2019 OUTBREAK) AGAINST THE DOCKING ANALYSIS WITH STRUCTURE PREDICTED HUMAN �ACE2-FC REGION OF IGG1� FUSION PROTEIN AS A PROTEIN BASED DRUG.", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.8, Issue 2, pp.1667-1675, February 2020, Available at :http://www.ijcrt.org/papers/IJCRT2002193.pdf
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
ISSN and 7.97 Impact Factor Details
ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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