Published Paper Details:

Abstract : Fat soluble vitamins are those which are dissolved in fat. Among the fat soluble vitamins, vitamin D is one of them. The main source of vitamin D is ultraviolet rays sunlight. Less amount of vitamin D is synthesized among dark skinned people than fair skinned people because the pigments within dark skin inhibit the entrance of ultraviolet radiation. Besides sunlight, humans can take vitamin D from diet. Vitamin D content foods are very few in nature. Some sea foods contain high amount of vitamin D3 like sardines, salmon and mackerel. . Some foods are fortified with vitamin D but the number of foods are very few. Some vitamin D fortified foods are cereals, some bread, milk and orange juice. The active form of vitamin D is 1,25-dyhydroxyvitamin D3 is known as to control calcium and phosphorus metabolism that is needed for healthy bone formation. Vitamin D has a another special role rather that formulating skeletal system. It act as a immune-modulator. It targets immune cells of various types like monocytes, macrophages, dendritic cells, as well as T and B lymphocytes, it control both innate and adaptive immunity. Now a days one of the major public health problem in India is Tuberculosis, a infectious bacterial disease named Mycobacterium Tuberculosis or MTB. Approximately 8.6 million TB cases were found globally and approximately 2 million TB cases were occurred in India. Underweight (BMI<18.5) means the weight less than normal weight. Underweight was observed in low economical group specially. Underweight is mainly seen in developing countries. A synergistic interaction was found between underweight and low level of vitamin D. It has been identified that maximum number of TB patients has very low body weight(underweight) Vitamin D is mainly beneficial for chronic infection like tuberculosis(TB). Deficiency of vitamin D occur when the people do not get enough ultraviolet B ray that come from sun light and another reason is that when the people do not get sufficient amount of vitamin D from the dietary sources. Most of the foods has very small amounts of vitamin D. Certain sea fishes are known as good sources of Vitamin D. Marine fishes should be incorporated in the diet. Fresh water fishes has moderate amount of vitamin D in their liver. Fortification of oil and wheat-flour with vitamin D may fill the gap of vitamin D deficiency.