Published Paper Details:

A series of rare earth metal complexes of Ce (III), Pr(III), Nd(III), Sm(III), Gd(III) and have been synthesized with newly synthesized biologically active macrocyclic ligand. The ligand was synthesized by condensation of ?-diketone 1-(4-chlorophenyl)-3-(2-hydroxyphenyl)propane-1,3-dione and 4-chlorobenzene-1,2-diamine. These complexes were characterized by various physico-analytical techniques, elemental analysis, molar conductivity, magnetic susceptibility, thermal analysis, X-ray diffraction, IR, 1H-NMR, electronic and mass spectroscopy. From the analytical data, stoichiometry of the complexes was found to be 1:1 (metal: ligand). Thermal behaviour (TG/DTA) analysis suggests more ordered activated state in complex formation. All the complexes are of high spin type and seven coordinated. The antibacterial and antifungal activities of the ligand and its metal complexes, has been screened in vitro against Staphylococcus aures, P. aeruginosa, M. luteus and Aspergillus niger, C. abicans respectively. All the complexes were found to be the more active than their parent ligand and metal salts.