Published Paper Details:

Hemoglobin is a major protein involved in transport of oxygen. Hemoglobinopathies are group of disease characterized by quantitative and/or qualitative abnormality in the production of Hemoglobin, e.g. thalassemia and sickle cell disease respectively. Identification of these disorders is immensely important epidemiologically and they can be prevented by population screening. Approximately 250 million people constituting 4.5% of the world population carry a potentially pathological haemoglobinopathy gene. Beta thalassemia are widely distributed through a belt running from Mediterranean, North West Africa through the Middle East, Pakistan, India and south East Asia. Hbs is prevalent in Africa, Mediterranean countries, and India. The disease is observed in Orissa, Andhra Pradesh, some tribal areas of Madhya Pradesh, Tamilnadu and Maharashtra. In USA and Latin America countries, 6-8% of the black carry sickle cells gene. The aim of the study was study of various Hemoglobinopathies in patients of Gujarat.