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According to Ayurveda, the body is made up of seven different types of tissues known as Sapta Dhatu. These seven tissues collaborate with one another to ensure that the human body functions perfectly physiologically. One of the seven Dhatus mentioned in Ayurveda is Asthi. We are attempting to compile information about Asthi Dhatu defined in unique texts in this article, covering everything from its formation to nutrition, number, nature, distribution, character, significance, and effects on the body when it deviates from its typical persona or wide variety, such as Asthi Kshaya and Asthi Vriddhi. Asthidhara Kala and Asthivaha Srotas are two other aspects of Asthi Dhatu that are also discussed. Asthi gives strength and stability, maintains posture, supports Majja Dhatu, and imparts compactness to the body in addition to shielding internal organs from external shock. Asthidhara Kala and Asthivaha Srotas, Asthi Marma, Asthi Sara, Asthi Pradoshaja Vikara are some other aspects of Asthi Dhatu that are also discussed. In the modern day, bones are the hard connective tissues that make up the majority of vertebrates' skeletons and are made of a collagen-rich natural matrix loaded with calcium, phosphate, and other minerals. Bones protect the body's organs, create red and white blood cells, store minerals, provide structure, help the body function, and provide mobility.