Published Paper Details:

Vitamin B12 deficiency is a serious health problem that can result in megaloblastic anemia, pernicious anemia, inhibition of cell division, and neurological disorders. Objective: Our study aims to identify the correlation between the deficiency of vitamin B12 and the hematological parameters, also the prevalence of vitamin B12 deficiency among vegetarian and non-vegetarian people of the city of Gujarat state. Method: Retrospective study undertaken among age varied from 18 to 60 years patients in Gujarat. 100 patients were studied and analyzed. Clinical features, hematological and serological parameters were noted. Result: We have evaluated the clinical picture, hematology indices of 100 patients with reduced vitamin B12 level. In this study secondary data on age, sex, referring unit, religion and dietary history of these patients were obtained from the medical laboratory Gujarat, India. We found the gender is significantly associated with hemoglobin. Vegetarian females have lower hemoglobin level than vegetarian males. Vitamin B12 deficiency is mainly mild to moderate (100 pg/ml-210 pg/ml). Severe B12 deficiency (100 pg/ml) is more involved in the younger age group (<50 years) than the older group (> 50 years). Conclusion: In our study, we concluded that the vegetarians have lower serum vitamin B12 levels compared to non-vegetarians. In present study total 100 patients were included and among them 48% were males and 52% were females. In which 28% males and 32% females were Vitamin B12 deficient. So, it is concluded that prevalence of vitamin B12 deficiency was higher in females as compared to male.