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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
Call For Paper - Volume 12 | Issue 5 | Month- May 2024
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Paper Title
FORMULATION AND EVALUTATION OF HYDROPHOBICS DRUG ROSUVASTATIN TABLET BY USING THE SOLID DISPERSION METHOD
Authors
Deepa Manohar Chandrawanshi, Dr. Manjeet Singh
Keywords
Solid dispersion method, Rosuvastatin tablet, Calibration curve, in vitro release profile.
Abstract
Solubility enhancement is a difficult task in to the formulation scientist because 80 percent of the drug having the poor boiavaiblity. For the formulation of the dosage form it is necessary to enhance the solubility of the drug. There is various techniques to enhance the solubility of the hydrophobic drugs such as kneading method, hot melt extrusion and solid dispersion. In this research work by using the solid dispersion method to enhance the solubility of rosuvastatin and convert in to the fixed dose of tablet formulation and its evaluation parameters formulation batches are to be design F1,F2,F3,F4,F5. Calibration curve are to be prepared or rosuvastatin pure form and scan at the lambda max 244 ?max. And obtain the r2 value 0.999 Formulation F5 shows better results and full fill all the parameter compare with the marketed formulation.
IJCRT's Publication Details
Unique Identification Number - IJCRT2303403
Paper ID - 232669
Page Number(s) - d491-d498
Pubished in - Volume 11 | Issue 3 | March 2023
DOI (Digital Object Identifier) - http://doi.one/10.1729/Journal.33356
Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Cite this article
Deepa Manohar Chandrawanshi, Dr. Manjeet Singh, "FORMULATION AND EVALUTATION OF HYDROPHOBICS DRUG ROSUVASTATIN TABLET BY USING THE SOLID DISPERSION METHOD", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.11, Issue 3, pp.d491-d498, March 2023, Available at :http://www.ijcrt.org/papers/IJCRT2303403.pdf
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
ISSN and 7.97 Impact Factor Details
ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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