Published Paper Details:

Oral sustained release (SR) products offer an advantage over traditional dosage forms by optimizing biopharmaceuticals, pharmacokinetic and pharmacodynamic properties of drugs to reduce the frequency of administration as much as possible once daily is sufficient for penetration, polymer swelling, drug dissolution, drug diffusion and matrix erosion. Superior water-soluble drugs such as diltiazem; Ranitidine is formulated in sustained-release matrix tablets. This article contains basic information on the design of slow-release preparations and their different types. Development, solid and sustained-release oral matrix tablet, has always been a challenge for the pharmaceutical technologist. Most drugs, if not properly formulated, can release, and likely produce the toxic drug concentration after oral administration. Hydrophilic polymers have become the preferred product as an important product Ingredient for formulating sustained release preparations.