Published Paper Details:

This review explores the important implications of the rising prevalence of the SARS-CoV-2 Omicron subvariant for public health . The XBB Omicron subvariant has demonstrated increased transmissibility through an apparent propensity for immune evasion All pandemic viruses have eventually adapted to human hosts so that they become more transmissible and less virulent. Our multiscale investigation provided evidence suggesting that XBB is the first documented SARS-CoV-2 variant increasing its fitness through recombination rather than single mutations. The XBB Omicron subvariant is rapidly becoming the dominant strain of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in October 2022 and is one of several variants circulating globally with the potential to dominate autumn/winter waves in different countries.. This is to be expected in the natural evolution of a virus in a population highly vaccinated with a vaccine targeting the spike protein of the original Wuhan strain of the virus.