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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
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Paper Title
HEPATOPROTECTIVE ACTIVITY OF LAGENARIA SICERARI EXTRACT AGAINST PARACETAMOL INDUCED HEPATIC DAMAGE IN RATS
Authors
Nagasree Thupakula, Dr. PrakashDr. Rakesh K J3, Dr. Rakesh K J
Keywords
Hepatoprotective Activity of Lagenaria sicerari Extract against Paracetamol Induced Hepatic Damage in Rats
Abstract
Lagenaria sicerari has been traditionally used in Indian medicine as a result of its curative results of hepatitis, gonorrhea and diabetes, it is probably not proof-founded. However folklore has given us many powerful therapies, based on plant sources. So claims which can be made for the protective efficacy of Lagenaria sicerari (family: Cucurbitaceae) to treat hepatic diseases. The present study focused on investigating the role of alcoholic extract of Lagenaria sicerari. It appreciably prevented the increased in serum Aspartate amino transferase (AST), Alanine amino transferase (ALT), alkaline phosphatase (ALP) and total serum bilirubin (SB) level in acute liver damage by Acetaminophen and elevated the activities of lipid peroxidation (LPO) and glutathione (GSH) in the liver. Histopathological observation of the liver used to be additionally performed to further support the evidence from the biochemical analysis. The observation that these significant protective effect against acute hepatotoxicity induced by acetaminophen of Lagenaria sicerari.
IJCRT's Publication Details
Unique Identification Number - IJCRT2301011
Paper ID - 229204
Page Number(s) - a84-a97
Pubished in - Volume 11 | Issue 1 | January 2023
DOI (Digital Object Identifier) -
Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Cite this article
Nagasree Thupakula, Dr. PrakashDr. Rakesh K J3, Dr. Rakesh K J, "HEPATOPROTECTIVE ACTIVITY OF LAGENARIA SICERARI EXTRACT AGAINST PARACETAMOL INDUCED HEPATIC DAMAGE IN RATS", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.11, Issue 1, pp.a84-a97, January 2023, Available at :http://www.ijcrt.org/papers/IJCRT2301011.pdf
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
ISSN and 7.97 Impact Factor Details
ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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