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  Published Paper Details:

  Paper Title

A REVIEW ON THERAPEUTIC APPLICATION OF RUTHENIUM COMPLEXES

  Authors

  Maruthachalam Mohanraj,  Pooja Rajagopalan,  Rayappan Rajkumar,  Ravikumar Raju

  Keywords

  Abstract


Abstract: To create a comprehensive treatment for cancer, the compound of cis-platin, a platinum compound, is particularly effective against malignancies and need to evolve a drug with minimum side effects. They have harmful effects on normal cells. As a result, the potential for additional components to act as anti-cancer agents was widely examined. Metal complexes such as Ru and Au demonstrated anti-cancer activity. Ru-complexes, in particular, were far more effective against cancer cells and had less adverse effects. Several Ru complexes, including Ru-Hydrazone complexes, Ru-Arene complexes, and Organo-Ru complexes, have been discovered to be highly effective against cancer cell development. NAMI-A (Trans-[RuCl4(DMSO)(Im)) and (KP1019)21 Indazolium trans-[tetrachlorobis(1H-indazole) ruthenate(III)] are two significant Ru complexes that have entered clinical trials, showing good tumour inhibition and minimal damage to normal cells. This is a brief overview of the various forms of Ru- complexes that operate as anticancer agents.

  IJCRT's Publication Details

  Unique Identification Number - IJCRT2211586

  Paper ID - 228323

  Page Number(s) - e900-e906

  Pubished in - Volume 10 | Issue 11 | November 2022

  DOI (Digital Object Identifier) -   

  Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882

  E-ISSN Number - 2320-2882

  Cite this article

  Maruthachalam Mohanraj,  Pooja Rajagopalan,  Rayappan Rajkumar,  Ravikumar Raju,   "A REVIEW ON THERAPEUTIC APPLICATION OF RUTHENIUM COMPLEXES", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.10, Issue 11, pp.e900-e906, November 2022, Available at :http://www.ijcrt.org/papers/IJCRT2211586.pdf

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ISSN: 2320-2882
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Journal Starting Year (ESTD) : 2013
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ISSN and 7.97 Impact Factor Details


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ISSN: 2320-2882
Impact Factor: 7.97 and ISSN APPROVED
Journal Starting Year (ESTD) : 2013
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