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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
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Paper Title
PREPARATION AND CHEMICAL ANALYSIS OF HYDROCHLOROTHIAZIDE TABLETS USING LIGNOCAINE HYDROCHLORIDE AS HYDROTROPIC AGENT
Authors
Dr. Pramod Kumar Singh, K.N.I.P.S.S. SultanpurK.N.I.P.S.S. Sultanpur, Ashish Dwivedi, Prashant Singh, Deo Saran Singh
Keywords
Hydrotropy, Hydrochlorothiazide, Lignocaine hydrochloride, Spectrophotometry.
Abstract
There was more that 50-fold enhancement in aqueous solubility of hydrochlorothiazide in 1 M lignocaine hydrochloride solution as compared to the solubility in distilled water. Therefore 1 M lignocaine hydrochloride solution was employed to extract out the drug from fine powder of the tablets of hydrochlorothiazide to carry out spectrophotometric estimation at 317 nm (Selected Wavelength). The hydrotropic agent and the additives used in the manufacture of tablets did not interfere in the analysis. Statistical data proved the accuracy, reproducibility and precision of proposed method.
IJCRT's Publication Details
Unique Identification Number - IJCRT2211040
Paper ID - 225957
Page Number(s) - a355-a358
Pubished in - Volume 10 | Issue 11 | November 2022
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Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Cite this article
Dr. Pramod Kumar Singh, K.N.I.P.S.S. SultanpurK.N.I.P.S.S. Sultanpur, Ashish Dwivedi, Prashant Singh, Deo Saran Singh, "PREPARATION AND CHEMICAL ANALYSIS OF HYDROCHLOROTHIAZIDE TABLETS USING LIGNOCAINE HYDROCHLORIDE AS HYDROTROPIC AGENT", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.10, Issue 11, pp.a355-a358, November 2022, Available at :http://www.ijcrt.org/papers/IJCRT2211040.pdf
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
ISSN and 7.97 Impact Factor Details
ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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