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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
Call For Paper - Volume 12 | Issue 5 | Month- May 2024
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Paper Title
HUMAN PAPILLOMAVIRUS (HPV) AND MODIFICATIONS BROUGHT IN THERAPEUTIC TREATMENTS: A PERSPECTIVE INSIGHT
Authors
DR. Anirban Chatterjee
Keywords
HPV, E6, E7, tumor-microenvironment
Abstract
Human papillomaviruses (HPVs) are small double-stranded DNA viruses that pose compelling public health concerns as the causative agent of approximately 5% of worldwide cancers. The HPV oncogenes E6 and E7 play fundamental roles in carcinogenesis. In the last 15 years, there has been a notable increase in the incidence of HPV-related head and neck cancers, arising primarily in the oropharynx. Patients with HPV-positive head and neck cancers (HNCs) have a significantly improved prognosis compared to those with HPV-negative disease. In this review, we will discuss data suggesting how HPV oncogenes modulate the intrinsic radiation sensitivity of HNCs and have important effects on the tumor microenvironment. Together, these findings contribute to the improved outcomes seen in patients with HPV-positive HNC.
IJCRT's Publication Details
Unique Identification Number - IJCRT2211017
Paper ID - 227080
Page Number(s) - a151-a156
Pubished in - Volume 10 | Issue 11 | November 2022
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Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Cite this article
DR. Anirban Chatterjee, "HUMAN PAPILLOMAVIRUS (HPV) AND MODIFICATIONS BROUGHT IN THERAPEUTIC TREATMENTS: A PERSPECTIVE INSIGHT", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.10, Issue 11, pp.a151-a156, November 2022, Available at :http://www.ijcrt.org/papers/IJCRT2211017.pdf
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
ISSN and 7.97 Impact Factor Details
ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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