Published Paper Details:

ABSTRACT: The whole world facing unpredictable problems with different variants of COVID-19; B.1.617.2 is the newest form of SARS- CoV-2.It is evolving through mutations to consistently being a risk to public health. Recently, the Delta variant has been declared as the variant of concern by the World Health Organization (WHO). Delta Plus has been presented to provide a relevant foundation for future research works. Mutations are causing SARS-CoV-2 to alter its genetic structure to improve its potential to elude the immune system, making vaccine build out against the virus more difficult. Multiple SARS-CoV-2 variants have been found up to this point; based on their impact on public health some are considered variants of concern (VOCs) and some are considered variants of interests. VOCs are linked to superior transmissibility, a decline in neutralization by natural or vaccine-induced antibodies, evading capability of detection, and a reduction in the efficacy of vaccines or therapeutics. In this article, a SARS-CoV-2 subtype, known as Delta, has been revised to provide the current state of the art and an appropriate foundation for future research works. The evolution, pathogenesis, current trends of transmission, associated symptoms, suggested prevention and treatments, and vaccine efficacy of the Delta variant are reviewed and discussed.