Published Paper Details:

The purposed study was to attempt the preparation of sustained released microspheres with thenatural polymers. The main obstacle in the preparation of the microsphere was the swelling ability and solubility of the banana flour that the microspheres. This restricts the preparation of microspheres of Venlafaxine HCL by simple techniques of double emulsion technique. In the present study the sustained release microspheres were attempted to prepare with Banana flour as a main natural polymer and xanthan gum, gaur gum as a co-polymer. The ionic gelation technique was used to prepare sustained release microspheres with Venlafaxine HCL. The prepared microspheres were characterized for scanning electron microscopy and micromeritic properties. Other studies like drug content, drug entrapment efficiency and drug release studies were also caried out. The resulting microspheres of batch V4 were found to be shown good at drug content , drug entrapment efficiency and also the drug release studies which was found to be 97.08%. From this study we can conclude that the microspheres can be prepared using banana powder as a natural polymer.