Published Paper Details:

Surgical site infections (SSIs) are a significant public health concern. In surgical infections, anaerobic bacteria are known to be major pathogens. Aerobes predominated over anaerobes in previous studies of bacteria detected in postoperative wounds. However, the epidemiology of SSI and the microorganisms that cause it are poorly understood, especially in eastern Nepal. As a result, the goal of this systematic review and meta-analysis has to assess the prevalence of anaerobic bacteria and associated variables in persons with post-operative wound infections in eastern Nepal. Pub Med, Google Scholar, Web of Science, Nepal Journals Online and Allied Health Literature for studies that reported the prevalence of postoperative anaerobic bacterial infections in people with SSI worldwide from January 1, 2000 to March 31, 2020. The 2 test on Cochran's Q statistic are used to assess heterogeneity, and H and I 2 statistics are used to quantify it. A random effect meta-analysis methodology is used to pool the prevalence data. To identify sources of heterogeneity in prevalence estimates, subgroup and Meta regression analyses are conducted. These works are described using the Preferred Reporting Items for Systematic Reviews and Meta Analyses (PRISMA) as a guideline. Since this study is based on published data, it does not require ethical approval. This systematic review and meta-analysis is intended to serve as a basis for determining the burden of anaerobic bacteria in SSIs for identifying data gaps and for guiding future investigations in Nepal. PROSPERO acknowledgement of receipt number is [265198].