Published Paper Details:

Parathyroid carcinoma is the rare type of endocrine malignancy. The causes of parathyroid carcinoma are unknown. Men and women are equally affected. The most effective method of treatment is surgical resection and palliation. Parathyroid carcinoma is progressive but slow growing. Pseudoparathyroidism is the severe complication. It comprises metabolic disorders which are characterized by physical findings. The physical findings variably include short bones, short stature, a stocky build early onset obesity and ectopic ossifications as well as endocrine defects that often include resistance to parathyroid hormone. Parathyroid glands are the two pairs of the small, oval-shaped glands. They are located next to the two thyroid gland lobes in the neck. Each gland is usually about the size of the pea. The management of parathyroid carcinoma is done on the basis of surgery, radiation therapy, chemotherapy. The management of hypercalcemia is done by using the agents such as biophosphonates, Plicamycin, Calcitonin, Gallium, Calcimimetics, WR-2721, Octreotide, Immunization.