Published Paper Details:

The marine environment is a huge reservoir of biodiversity and represents an excellent source of chemical compound, some of which large economical values. Today the structures of around 1,40,000 secondary metabolites have been elucidated. Marine based drug discovery has progressed significantly over the past several decades. Recent advances in extraction and isolating techniques, and in state of the art technologies involved in organic synthesis and chemical structure elucidation, have accelerated the numbers of antimicrobial molecules originating from the ocean moving into clinical trials. These natural products have been categorized based on their chemical structures and the structure activity mediated relationships of some of these bioactive molecules have been discussed. Detailed accounts are also given on novel marine metabolites, were isolated from different (sponges, micro-organisms, seaweeds, fishes, cones) sources. (a part from that, we covered the role of natural products in disease, treatment and commercial utilization of the compound). This review article gives knowledge about the discovery, source, and future prospects of some of the marine drugs.