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Introduction In ancient Ayurvedic literature, the names Vyadhi and Roga are the most commonly used terminology for disease or illness. Diseases are given many different names in Ayurveda, such as Vikara, abadha, 'papa-dukha,' amaya, yaksma, gada, atanka, and so on. All of these names have been given to Rogas because of their impact on the somatic, psychological, karmic, and metaphysical levels. The location or base (Adhisthana) of illnesses, according to Charka, is the mind (manas) and body (sharira), as well as the senses (Indriyas) (vedana). Manas Vikara is recognized as triggering variables of psychosomatic disorder in this context. Charaka has identified three elements that are responsible for the onset of sickness. Methodology - The material of manas Vikara collected from various authentic articles, literature, websites etc. Discussion Ayurveda describes several ailments that are primarily caused by mana yet manifest as systemic symptoms. Shokaja Jwara, Kamaj jvara, Krodhaja jvara, Bhayaja atisara, Shokaja atisara, and so on are names based on the involved Manasika Vikara. Conclusion Psychosomatic disorders are medical illnesses that are linked to a psychological condition. A psychosomatic disease is a physical ailment that is defined by an intrinsic structural change in the body that is induced or made worse by stress.