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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
Call For Paper - Volume 12 | Issue 5 | Month- May 2024
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Paper Title
CYCLIC VOLTAMETRIC AND DNA CLEAVAGE STUDIES OF INDOLYL CARBOHYDRAZIDES
Authors
Dr. Parveen Rajesab, Dr.J.S. Biradar, Dr. Jaishree Badiger
Keywords
Indole, Carbohydrazide, DNA Cleavage activity, Cyclicvoltametry
Abstract
The indole analogues were investigated for the electrochemical behavior using the glassy carbon electrode as the working electrode. In the present study electrochemical reduction or oxidation of indole analogues in sulphuric acid media was reported. We can see that the C=N functional groups in the molecule is easily reduced at the glassy carbon electrode. These compounds were also subjected to DNA cleavage study. In this study Compounds 1a-c have shown highest activity and remaining compounds shown moderate activity. Compounds with halogen, methyl substitution at five positions and phenyl ring at third position of indole nucleus have exhibited very good activity when compared to standard.
IJCRT's Publication Details
Unique Identification Number - IJCRT2201422
Paper ID - 215246
Page Number(s) - d770-d775
Pubished in - Volume 10 | Issue 1 | January 2022
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Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Cite this article
Dr. Parveen Rajesab, Dr.J.S. Biradar, Dr. Jaishree Badiger, "CYCLIC VOLTAMETRIC AND DNA CLEAVAGE STUDIES OF INDOLYL CARBOHYDRAZIDES", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.10, Issue 1, pp.d770-d775, January 2022, Available at :http://www.ijcrt.org/papers/IJCRT2201422.pdf
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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