Published Paper Details:

The aim & objective of the research is to evaluate the synergistic anti diabetic activity of polyherbal drugs containing Gymnema Sylvestre (Leaves),Trigonella Foenum-Gr (Leaves), Tinospora Cardifolia (Stems), Azadirachata Indica (Leaves), Cinnamomum Zeylanicum (Stem Barks), Syzygium Jambolana (Fruits) & Nardostachys Jatamansi (Roots) which are well-known medicinal plants available throughout India and they are commonly used for the treatment of various diseases. All the herbal drugs were collected from herbal shop (Grovel Drugs & Chemicals Pvt Ltd.Hyderabad). The quality of the finished product was evaluated as per the World Health Organization's guidelines for the quality control of herbal materials. The quality testing parameters of the herbal drugs were within the limits. The developed polyherbal formulation is subjected for extraction with ethanol (90%) by cold maceration & soxhelation method to get ethanolic extract. The polyherbal ethanolic extract is evaluated for its antidiabetic and antioxidant activity. Screening of preliminary phytochemical investigation of polyherbal ethanolic extract shows the presence of large amounts of phenolic, tannins & flavonoid compounds which exhibits the highest antioxidant and free radical scavenging and also inhibited lipid peroxidation. The polyherbal extract shows synergistic effect of antidiabetic activity and it may be used as an alternative remedy for the treatment of diabetes mellitus.