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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
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Paper Title
A PROTECTIVE STATUS OF HBSAG AND ANTI-HBS IN VACCINATED NEWBORNS FROM HEPATITIS B POSITIVED MOTHERS: A META-ANALYSIS
Authors
Indah Lestari, Bagus Setyoboedi, Martono Tri Utomo
Keywords
anti-HBs, HBsAg, hepatitis B, meta analysis
Abstract
Background: Mother-to-child transmission of hepatitis B virus makes a significant contribution to chronic hepatitis B virus infection. One strategy to prevent hepatitis B transmission from mother to child is by administering hepatitis B immunoglobulin (HBIg) and hepatitis B vaccination.
Methods: This meta-analysis used secondary data from articles taken from 2000 to 2020 through the PubMed database, Google Scholar. There were 5 articles for antiHbs and 4 articles for HBsAg that matched the inclusion and exclusion criteria. Analysis using the Revman Review Manager 5.4.
Results: The comparison of the proportion and confidence interval on HBsAg and anti-HBs status after hepatitis B vaccination in infants of HBsAg positive mothers showed that anti-HBs results with a combined effect magnitude of 0.89 (95% CI 0.83; 0.94), p < 0.05 while HBsAg status with a combined effect of 0.09 (95% CI 0.03; 0.015), p < 0.05.
Conclusion: The successful proportion of hepatitis B vaccination with HbIg is 89% and HbsAg positive status in infants is 9%.
IJCRT's Publication Details
Unique Identification Number - IJCRT2108059
Paper ID - 210768
Page Number(s) - a479-a487
Pubished in - Volume 9 | Issue 8 | August 2021
DOI (Digital Object Identifier) -
Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Cite this article
Indah Lestari, Bagus Setyoboedi, Martono Tri Utomo, "A PROTECTIVE STATUS OF HBSAG AND ANTI-HBS IN VACCINATED NEWBORNS FROM HEPATITIS B POSITIVED MOTHERS: A META-ANALYSIS", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.9, Issue 8, pp.a479-a487, August 2021, Available at :http://www.ijcrt.org/papers/IJCRT2108059.pdf
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
ISSN and 7.97 Impact Factor Details
ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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