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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
Call For Paper - Volume 12 | Issue 5 | Month- May 2024
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Published Paper Details:
Paper Title
FORMULATION AND EVALUATION OF SOLID DISPERSION INCORPORATED FAST DISINTEGRATING TABLET OF ANTIEMETIC DRUG.
Authors
Himani Jaisinghani, Nadeem Farooqui, Dinesh Kumar Mishra
Keywords
Solubility, Solid dispersion, Fast disintegrating tablet, Aprepitant.
Abstract
In the present work, the aim is to successfully formulate solid dispersion and incorporated it into a fast disintegrating tablet of aprepitant. Firstly increases the solubility of poorly water-soluble aprepitant by solid dispersion and then it is formulated into FDTs with improved patient compliance and convenience. Solid dispersions are prepared by the fusion method and solvent evaporation method. The formulation F9 is selected for best formulation because it shows the % yield 95%, drug content, dissolution 94%. after then selected batch F9 is formulated into FDTs results are disintegration time 12 seconds, dissolution drug release 99 % of this formulation respectively.
IJCRT's Publication Details
Unique Identification Number - IJCRT2106347
Paper ID - 207830
Page Number(s) - d23-d41
Pubished in - Volume 9 | Issue 6 | June 2021
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Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Cite this article
Himani Jaisinghani, Nadeem Farooqui, Dinesh Kumar Mishra, "FORMULATION AND EVALUATION OF SOLID DISPERSION INCORPORATED FAST DISINTEGRATING TABLET OF ANTIEMETIC DRUG.", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.9, Issue 6, pp.d23-d41, June 2021, Available at :http://www.ijcrt.org/papers/IJCRT2106347.pdf
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
ISSN and 7.97 Impact Factor Details
ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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