Published Paper Details:

Background: Bronchial Asthma most common chronic, non-communicable diseases in adults due to involvement of various cellular populations and important cause of morbidity and mortality in India and abroad. Due to wide variations among different asthmatics there is a need for a specific bio-marker to diagnose and prognoses the asthma conditions. Method: 80 (eighty) Bronchial asthma patients aged between 35 to 65 were studied and compared with healthy voluntary of same number. Pulmonary function test, Blood examination for peripheral Eosinophlia, IgE and Sputum for Eosinophia chest X-ray was performed to confirm and diagnose. Results: History of smokers, allergic rhinitis and family history were higher in Bronchial asthma patients. The parameters like IgE, peripheral Eosinophilia %, sputum Eosinophilia, FVC% predicted FEV1, FEV1/FVC predicted, post FVC/post FEV1 predicted had significant P value (P<0.001) when compared with controlled group. Conclusion: This correlative study of peripheral Eosinophilia, Sputum Eosinophilia, IgE, and FEV1 will be the tolls for the clinician to predict the prognosis and treat efficiently to avoid morbidity and mortality.