Published Paper Details:

Abstract Molecular hybridization of nucleic acids is the process in which two single-stranded nucleic acid molecules with complementary base sequences form a double-stranded nucleic acid molecule. Nucleic acid hybridization technology is a fundamental tool in molecular biology, and has been applied in various fields such as detection of gene expression, screening specific clone from cDNA or genomic library, determining the location of a gene in chromosome and diagnosis of diseases. Cage like property for eg graphene or glue like bio material from spider or even polymer can bind rapid growth of cell for its binding nature at micro level or can trap bacterial or viral growth by trapping within Net like structure. The idea of Quantum Dots may be implied to identify such net as drug to separate from diseases infected Zone. Sometime electrification or by application of Radioactivity through this net may reduce harmful diseases spreading. Molecular hybridization a useful tool in the design, trapping of new generation drug prototypes using the sequencing of Nucleic acids for a particular patient. Molecular hybridization is a new concept in drug design and development based on the combination of pharmacophoric moieties of different bioactive substances to produce a new hybrid compound with improved affinity and efficacy, when compared to the parent drugs. Additionally, this strategy can result in compounds presenting modified selectivity profile, different and/or dual modes of action and reduced undesired side effects. So, in this paper, we described several examples of different strategies for drug design, discovery and pharmaco modulation focused on new innovative hybrid compounds presenting analgesic, anti-inflammatory, platelet anti-aggregating, anti-infectious, anticancer, cardio- and neuroactive properties. By this molecular hybridization concept in the field of genetic engineering and as well as molecular biology, formation of a partially or wholly complementary nucleic acid duplex as association of single strands, usually between DNA and RNA strands (previously associated or un associated DNA , RNA strands.). These are used to detect an isolated specific genetically initiated sequences as measured sequencing homology, or define other characteristics of one or both strands. If we can detect the particular cause of critical disease like Parkinson, Cancer or AIDS for a particular patient. We can synthesis the new drug design for that patient to treat them for complete cure in this molecular hybridisation concept. So this is a new generation concept for developing drug as well as the cause of the particular diseases for a particular patient. Not only that by fusing more than one drugs structure components by Molecular hybridisation concept we can make a single drug for a patient with multiple affected diseases using computer simulation more modern method in the field of medicinal chemistry. The idea will show us to find the way of sustainable health and immortality in future.