Published Paper Details:

Cellular DNA may damaged when exposed to harmful Ultraviolet rays for long duration. More energetic UV-B rays causes harm to cells by producing chemical changes in molecules, especially proteins and nucleic acids. To analyze the effect of UV rays Calf thymus DNA and prevention by polyphenol enriched extract of Drum stick (Moringa oleifera) leaves and also its non toxic nature. The above study was done by using submarine gel electrophoresis where UV rays are used to damage the DNA and Ascorbic acid (400�M) used as positive control. The polyphenol enriched extract was taken at 15?g concentration prevent UV rays induced DNA fragmentation in submarine agarose gel electrophoresis which provides protection when compared to standard antioxidant Ascorbic acid (400?M). The cytotoxicity studies showed that, the extract and Ascorbic acid provides a protection of 59% whereas, the extract of Drum sticks leaves showed 69%. In conclusion, the Drum stick leaves extract showed a promising DNA protectant activity against UV rays induced DNA damage.