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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
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Published Paper Details:
Paper Title
A REVIEW OF CHEMICAL CONSTITUENTS FROM THE ROOTS OF CASSIA AURICULATA LINN
Authors
Dr. Yashwant Ray BalWant
Keywords
Keywords: Cassia auriculata; Cisplatin; Gentamicin; Nephrotoxicity; Nephroprotection
Abstract
Abstract :- The ethanol extract of the roots of Cassia auriculata was studied for its nephroprotective activity in cisplatin- and gentamicin-induced renal injury in male albino rats. In the cisplatin model, the extract at doses of 300 and 600 mg/kg body wt. reduced elevated blood urea and serum creatinine and normalized the histopathological changes in the curative regimen. In the gentamicin model, the ethanol extract at a dose of 600 mg/kg body wt. reduced blood urea and serum creatinine effectively in both the curative and the preventive regimen. The extract had a marked nitric oxide free-radical-scavenging effect. The findings suggest that the probable mechanism of nephroprotection by C. auriculata against cisplatin- and gentamicin-induced renal injury could be due to its antioxidant and free-radical-scavenging property.
IJCRT's Publication Details
Unique Identification Number - IJCRT2011140
Paper ID - 200283
Page Number(s) - 1147-1149
Pubished in - Volume 8 | Issue 11 | November 2020
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Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Cite this article
Dr. Yashwant Ray BalWant, "A REVIEW OF CHEMICAL CONSTITUENTS FROM THE ROOTS OF CASSIA AURICULATA LINN", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.8, Issue 11, pp.1147-1149, November 2020, Available at :http://www.ijcrt.org/papers/IJCRT2011140.pdf
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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