Published Paper Details:

Amongst the numerous carrier�s rejected for aiming drugs to numerous body nerves, the cellular carriers encounter several standard�s required in clinical applications, among the most important being biocompatibility of carrier as well its dilapidation products. Leucocytes, platelets, erythrocytes, Nano erythrocytes, hepatocytes, and fibroblasts etc. have been proposed as cellular carrier structures. Among these, the erythrocytes have been the most explored and have found to own better potential in drug delivery. Bio-pharmaceuticals, intensely significant peptides and proteins, antigens, anticancer drug as well as vaccines, are among the freshly attentive pharmaceuticals for being transported using carrier erythrocytes. Erythrocytes, better known as red blood cells, and have been broadly studied for their potential carrier capabilities for the delivery of drugs. The biocompatibility, non-pathogenicity, non-immunogenicity and biodegradability make them unique and useful carriers. Carrier erythrocytes are prepared by gathering blood sample from the organism of interest and separating erythrocytes from plasma. Via some methods, the cells are fragmented and the drug is hooked on the erythrocytes, finally they are resealed and the resulting carriers are then called as "resealed erythrocytes". So many drugs like aspirin, steroid, cancer drug which having many side effects are decrease by resealed erythrocyte. Current review highlights erythrocytes, drug loading methods, in vitro characterisation, application, advantages as well as disadvantages of resealed erythrocytes for drug delivery.