Published Paper Details:

Skin is the constitutional and largest organ of the human body and also manageable organ of human body. The outermost layer of the skin stratum corneum (SC) causes a barrier for high molecular weight drug and hydrophilic drugs. Trans Dermal Drug Delivery system (TDDS) are the dosage form which are self-reliant ,distinct dosage form which reaches the system circulation when applied to the skin thus first pass metabolism. The objective of TDDS is to cross the stratum corneum (SC) for which various methods have been used to increase the penetration of the drugs into the skin this reaching the system circulation. Ethosomes are the most promising or pioneering novel drug delivery system. Ethosomes are the novel drug delivery system which contain high concentration of ethanol and water thus which improves the bioavailability and skin permeability. Ethosomes are the novel phospholipids carriers which enable the drugs to reach the blood circulation which are made up of phospholipids. This article focuses on advantages , disadvantages, preparation method, its dosage form such as gels, patches, and creams . Method of characterization parameters are highlighted such as vesicle size, zeta potential, size distribution etc. Ethosomes are innovative carriers for delivery of therapeutic agents