Published Paper Details:

Dengue virus infection may manifest clinically as undifferentiated fever, dengue fever (DF), dengue haemorrhagic fever (DHF) or dengue shock syndrome (DSS). Renal injury has been reported in dengue patients. Aim: To evaluate the renal involvement in dengue fever. Methods: 100 patients of dengue were evaluated who were admitted in Chittagong medical college hospital. Socio demographic, clinical biochemical and serological analysis were done. Results were analyzed by SPSS and p value considered significant when it was <0.05. Results: Among the 100 patients of dengue urine albumin was found among 55% of patients, urine RBC was found in 31% of patients, urine pus cell was found in 3% patients and urine cast was found in 6% of patients, blood urea was 35 � 10.663 mg/dl and serum creatinine 1.39� 0.307 mg/dl. Among the 100 patients 82% patients improved, 11% patients were referred to different wards, 5% patients refused present hospital treatment and 2% patient died. Among the 82 improved patients mean � SD of blood urea was 22.99 � 8.085 mg/dl and creatinine was 1.359 � .283 mg/dl. Patients who were referred and died also had mean � SD of serum creatinine were 1.35 � 0.212mg/dl and 1.6 � 0.404 mg/dl and mean � SD urea were 38.45 � 13.14 mg/dl and 50 � 14.24 mg/dl respectively. Regarding analysis of renal involvement, >40mg/dl urea was found among 35(35%) patients whereas serum creatinine was found >1.2mg/dl among 27(27%) of patients and <3gm/dl serum albumin was found among 7(7%). Azotemia was associated with high level of mortality which was statistically significant (p<0.05). Conclusion: Dengue is a common viral disease in this area and renal involvement is also a common findings among the patients of dengue