Published Paper Details:

Pyrazolines are prominent nitrogen-containing heterocyclic compounds and hence, various procedures have been accomplished for their synthesis. Fischer and Knoevenagel i.e. the reaction of ?, ?-unsaturated ketones treat with phenylhydrazine in acetic acid under refluxing condition. it is one of the most popular methods instead of other various methods for the synthesis of pyrazolines. Though, They had synthesized the pyrazolines under various solvent media and acidic or basic conditions based on the reactivity of molecules and the need of the chemist. The synthesis of novel pyrazoline derivatives and the investigation of their chemical and biological behavior has gained more importance in recent decades. Earlier, modifications of the pyrazoline ring have proven highly effective along the improved potency and lesser toxicity. The analyzed review provides an accelerated view of work done so far on pyrazoline and its biological activities covering anticancer, antimycobacterial, antimicrobial, anticonvulsant, anti-inflammatory, and antitubercular activities.