Published Paper Details:

Convalescent plasma (CP) medical care, a classic adaptive therapy, have been applied to the hindrance and treatment of many infectious diseases for over one century. Over the past 20 years, CP medical care was with success utilized in the treatment of respiratory disease, MERS, and 2009 H1N1 pandemic with satisfactory effectiveness and safety. Since the medicine and clinical characteristics share similarity among respiratory disease, Middle East Respiratory Syndrome (MERS), and COVID-19, CP medical care may be a promising treatment choice for COVID-19 rescue. Patients who recovered from COVID-19 with a high neutralizing protein concentration could also be a valuable donor supply of CP. However, the CP medical care was unable to considerably improve the survival within the Ebola sickness, most likely because of the absence of information of neutralizing protein volumetric analysis for stratified analysis. In US, FDA declared an emergency IND (eIND) method to permit individual physicians to treat patients with serious COVID-19 sickness with convalescent plasma collected by a blood centre. This method is the furthest on New York City, wherever many hospitals square measure getting down to utilize this eIND method. Recently, the FDA declared a partnership with the Mayo Clinic and also the American NGO to gather and distribute plasma across the country via a master protocol for patients with severe or dangerous infection. Lastly, tutorial investigators have submitted multi-centre clinical trials for FDA approval, that specialize in bar of bad people, treatment of these with gentle sickness, treatment of these with serious however not important COVID-19 sickness, or treatment of critically-ill unit patients. Similar efforts square measure current around the world. the utilization of convalescent plasma is associate degree interim approach, whereas, vaccines and effective drug therapies are developed. Recently, Kerala possesses the Indian Council of Medical analysis (ICMR) approval for the clinical protocol exploring the practicability of convalescent plasma transfusion which can be administered to severe Covid- 19 patients. This study is regarding the effectiveness of plasma medical care in treating COVID -19, challenges and opportunities of plasma medical care and viability of plasma medical care in India.