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  Published Paper Details:

  Paper Title

APPLICATIONS OF IMMUNOGLOBULIN ISOTYPES IN CANCER IMMUNOTHERAPY - A REVIEW

  Authors

  Sruthi Menon,  Siddhi Bhutada,  Dhruv Bhatia

  Keywords

Cancer Immunotherapy, antibodies, IgG, IgE, IgA, IgM.

  Abstract


Immunoglobulins form a very crucial part of cancer immunotherapy. Stimulating host tumour-antigen-specific immune responses such as induction of antibody-dependent cellular cytotoxicity, promotion of antibody-targeted cross-presentation of tumour antigens, activation and degranulation of immune effector cells and complement based cell destruction is the most essential role of immunoglobulins in cancer treatment. This review discusses the potentials of the different isotypes of antibodies - IgG, IgE, IgA and IgM in cancer therapy. It also gives insights of current treatment modifications and combinations which can further be studied in order to prolong and amplify immune responses to increase the clinical benefits of antibody therapy for human cancer.

  IJCRT's Publication Details

  Unique Identification Number - IJCRT2005028

  Paper ID - 193936

  Page Number(s) - 185-189

  Pubished in - Volume 8 | Issue 5 | May 2020

  DOI (Digital Object Identifier) -   

  Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882

  E-ISSN Number - 2320-2882

  Cite this article

  Sruthi Menon,  Siddhi Bhutada,  Dhruv Bhatia,   "APPLICATIONS OF IMMUNOGLOBULIN ISOTYPES IN CANCER IMMUNOTHERAPY - A REVIEW", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.8, Issue 5, pp.185-189, May 2020, Available at :http://www.ijcrt.org/papers/IJCRT2005028.pdf

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ISSN: 2320-2882
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ISSN and 7.97 Impact Factor Details


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ISSN
ISSN: 2320-2882
Impact Factor: 7.97 and ISSN APPROVED
Journal Starting Year (ESTD) : 2013
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