Published Paper Details:

ABSTRACT Objective: To determine the Statin (Fluvastatin) in pure form simple and cost effective spectrophotometric method was developed. Methods: The UV spectrum of Fluvastatin in methanol showed absorption maximum at 304 nm and obeys beer�s law in the concentration range 5-30 �g/ml. The absorbance was found to be increases concentration with increasing linearity which is calculated by correlation coefficient value of 0.998. This method was validated for the accuracy, linearity, precision, ruggedness and robustness. Results: The method has demonstrated excellent linearity over the range of 5-30 �g/ml with regression equation y = 0.022x + 0.053 and regression coefficient r2 = 0.998. Furthermore, the method was found to be highly sensitive with LOD (1.501�g/ml) and LOQ (4.550�g/ml) Conclusion: On the basis of the results, this method was successfully applied for the assay of Fluvastatin in different pharmaceutical dosage forms.