Published Paper Details:

Albizzia procera (Roxb.) Benth. belonging to the family Fabaceae is widely distributed from India and Myanmar through Southeast Asia to Papua New Guinea and northern Australia. This plant is commonly used for the treatment of various ailments in Siddha system of medicine. All parts of this plant are reported to show anti-cancer activity. They were reported to exhibit various pharmacological activities such as CNS activity, cardiotonic activity, lipid-lowering activity, anti-oxidant activity, hepatoprotective activity, hypoglycemic activity, etc. The roots contain ?-spinasterol and a saponin that has been reported to possess spermicidal activity at a dilution of 0.008%. Though the root of A. procera is used as medicine in the traditional systems, no scientific data is available to identify the genuine sample. The present investigation was therefore taken up to establish identity of the root of the plant morphologically, microscopically, physico-chemically, chromatographically and spectroscopically for the standardization of the drug. Diagnostic features by macroscopic and microscopic examinations not only confirm the true identity of the drug but also help in detecting any adulterant or substitute. Physico-chemical parameters like loss on drying at 105?C, total ash, acid insoluble ash, water soluble extractives and alcohol soluble extractives of the root powder were carried out. The HPTLC profile may serve as a characteristic fingerprint for qualitative evaluation. Spectroscopic technique like UV-Vis can be successfully used alone or with other methods for standardization purpose. The results achieved from all types of analysis performed will be useful for authentication, standardization and quality control assessment of the root of Albizzia procera.