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  Published Paper Details:

  Paper Title

INHIBITION OF CALCIUM OXALATE CRYSTALLISATION IN VITRO BY AN EXTRACT OF LANTANA CAMARA

  Authors

  Dr.J.Uthaya Chandirika,  Dr.G.Annadurai

  Keywords

Lithiasis, Nucleation , Lantana camara, Urolithiasis, phytochemicals

  Abstract


To study the potency of aqueous extracts found from Lantana camara (family Verbenaceae) on calcium oxalate crystallization in vitro and the present study is aimed to determine the phytochemical screening Calcium oxalate crystallization was induced by the addition of 0.01 M sodium oxalate solutions. The effect of extract (0.2, 0.4, 0.6, 0.8 and 1 mg/ml) was studied by the measuring of turbidity in presence or absence of extract at 620 nm of a spectrophotometer. The herb extract of Lantana camara promoted the nucleation of calcium oxalate crystals, raising their amount but decreasing their size. It also promoted the formation of calcium oxalate dehydrates crystal, despite the presence of calcium oxalate monohydrate particles. Preliminary phytochemical screening of different extracts of Lantana camara revealed the presence of Alkaloids, Saponins, Glycosides, Carbohydrate, Tannins, Flavonoids, Steroids, Triterpenoids, fixed oil and fates. An outcome obtained showed that aqueous extract of leaf has the higher capacity to inhibit the crystal organisation and aggregation as compared to cystone we expected this investigation would provide encouragement for further exploration into new drugs for the prevention and treatment of urolithiasis, this plant may be explored therapeutic agent in future.

  IJCRT's Publication Details

  Unique Identification Number - IJCRT1705174

  Paper ID - 180702

  Page Number(s) - 1188-1199

  Pubished in - Volume 6 | Issue 1 | January 2018

  DOI (Digital Object Identifier) -   

  Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882

  E-ISSN Number - 2320-2882

  Cite this article

  Dr.J.Uthaya Chandirika,  Dr.G.Annadurai,   "INHIBITION OF CALCIUM OXALATE CRYSTALLISATION IN VITRO BY AN EXTRACT OF LANTANA CAMARA", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.6, Issue 1, pp.1188-1199, January 2018, Available at :http://www.ijcrt.org/papers/IJCRT1705174.pdf

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ISSN: 2320-2882
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ISSN and 7.97 Impact Factor Details


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ISSN: 2320-2882
Impact Factor: 7.97 and ISSN APPROVED
Journal Starting Year (ESTD) : 2013
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