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Comparative literature Review of Neurodegenerative disorder: Parkinson's disease and Kampavata.
Authors
Dr. Nikita Narayan Basatwar,Prof. Dr. Manjiri Sadanand Deshpande
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Keywords
Parkinson's disease, neurodegenerative disorders, Ayurveda, Kampavata and Vata dosha.
Abstract
Introduction: Neurodegenerative disorders, including Parkinson's disease (PD), are characterized by the progressive deterioration of neuronal structure and function, leading to motor and cognitive impairment. Parkinson's disease, prevalent among older adults, involves the degeneration of dopaminergic neurons in the substantia nigra, resulting in symptoms like tremors and rigidity. Ayurveda conceptualizes Parkinson's as "Kampavata," a disorder linked to an imbalance in the Vata dosha.
Aim: To compare the neurodegenerative disorder Parkinson's disease and Kampavata through literature review.
Method: This review synthesizes findings from classical Ayurvedic texts such as the Charaka Samhita and modern scientific research on neurodegeneration and Parkinson's disease. Comparative analysis of Ayurvedic and modern pathology was conducted, emphasizing the progression and underlying mechanisms of neurodegenerative disorders.
Discussions: In modern medicine, neurodegenerative disorders result from the progressive loss of neurons, with Parkinson's disease characterized by dopaminergic neuron degeneration and alpha-synuclein aggregation. Similarly, Ayurveda attributes Parkinson's disease to Majja Dhatu (nervous tissue) depletion due to Vata imbalance (Ruksha guna), leading to motor dysfunction. Aging, lifestyle factors, and oxidative stress exacerbate this degeneration. Ayurvedic concepts of Ama (metabolic toxins) align with alpha-synuclein aggregation in PD, linking impaired metabolism to neuronal dysfunction. Ayurveda offers a holistic view of neurodegeneration, correlating with modern understandings of neuronal loss, oxidative stress, and lifestyle impacts on Parkinson's disease. Both systems emphasize aging as a key factor, with Ayurveda focusing on Vata imbalance (vyana and udana vayu) and modern science on cellular stress mechanisms.
Conclusion: In Conclusion the Ayurvedic model of neurodegeneration aligns with modern pathology in recognizing the interplay of aging, lifestyle, and neurodegeneration. This integrative framework highlights Ayurveda's potential to enrich modern perspectives on Parkinson's pathology, warranting further research to bridge traditional and modern medical insights.
IJCRT's Publication Details
Unique Identification Number - IJCRT2411115
Paper ID - 271687
Author type - Indian Author
Page Number(s) - b40-b45
Pubished in - Volume 12 | Issue 11 | November 2024
DOI (Digital Object Identifier) -
No Of Downloads - 292
Author Country - India, 411011, Pune, Pune, 411011, Humanities All
Publisher Name - IJPUBLICATION | www.ijcrt.org | ISSN : 2320-2882
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Dr. Nikita Narayan Basatwar,Prof. Dr. Manjiri Sadanand Deshpande, "Comparative literature Review of Neurodegenerative disorder: Parkinson's disease and Kampavata.", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.12, Issue 11, pp.b40-b45, November 2024, Available at :http://www.ijcrt.org/papers/IJCRT2411115.pdf
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