ISSN2320-2882
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Paper Title
Diabetic Ketoacidosis Unveiling Hypertriglyceridemia-Induced Acute Pancreatitis With Concurrent Bacteraemia In A Young Adult: A Complex Multi-System Presentation
Authors
Dr Abhiraj Parmar , Dr Roshni Sadaria , Dr Ronak Shah
Keywords
Diabetic Ketoacidosis; Hypertriglyceridemia; Pancreatitis, Acute; Bacteremia; Diabetes Mellitus Type 1; C-Peptide; Serratia marcescens; SPICE organisms
Abstract
Abstract: Background: The simultaneous occurrence of diabetic ketoacidosis (DKA), hypertriglyceridemia-induced acute pancreatitis (HIAP), and Gram-negative bacteraemia represents an exceptionally rare and clinically challenging constellation in young adults. The triad demands meticulous diagnostic reasoning because each condition can mask or mimic the others.
Case Summary: A 25-year-old male with no prior documented diabetes mellitus presented to the emergency department with a three-day history of progressive altered sensorium, breathlessness at rest (MMRC Grade IV), diffuse chest pain, low-grade fever, inability to ambulate, and bowel and bladder incontinence. Investigations confirmed DKA, markedly elevated pancreatic enzymes (serum amylase 597 U/L; serum lipase 235 U/L), bilateral pleural effusions, ascites, and blood culture positivity for Serratia marcescens. A critically depressed C-peptide level (0.14 ng/mL) was consistent with new-onset Type 1 Diabetes Mellitus. The patient was managed in the medical intensive care unit (MICU) with aggressive intravenous fluid resuscitation, insulin infusion, electrolyte replacement, and targeted antimicrobial therapy.
Conclusion: This case underscores the importance of a broad diagnostic approach in DKA, particularly the measurement of serum triglycerides, lipase, and amylase, as HIAP may perpetuate DKA in a vicious cycle. Concurrent Gram-negative bacteraemia further compounds morbidity and mandates early blood cultures with targeted therapy. Awareness of this triad can significantly alter the management strategy and improve outcomes.
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IJCRT — journal style
"Diabetic Ketoacidosis Unveiling Hypertriglyceridemia-Induced Acute Pancreatitis With Concurrent Bacteraemia In A Young Adult: A Complex Multi-System Presentation", IJCRT - International Journal of Creative Research Thoughts (www.ijcrt.org), ISSN:2320-2882, Vol.14, Issue 5, page no.b277-b282, May 2026, Available :https://ijcrt.org/papers/IJCRT2605165.pdf
APA — 7th edition
Parmar, A., Sadaria, R., & Shah, R. (2026). Diabetic Ketoacidosis Unveiling Hypertriglyceridemia-Induced Acute Pancreatitis With Concurrent Bacteraemia In A Young Adult: A Complex Multi-System Presentation. International Journal of Creative Research Thoughts, 14(5), b277-b282. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2605165
MLA — 9th edition
Parmar, Abhiraj, et al. "Diabetic Ketoacidosis Unveiling Hypertriglyceridemia-Induced Acute Pancreatitis With Concurrent Bacteraemia In A Young Adult: A Complex Multi-System Presentation." International Journal of Creative Research Thoughts, vol. 14, no. 5, 2026, pp. b277-b282, https://ijcrt.org/viewpaperforall.php?paper=IJCRT2605165.
Chicago — 17th, bibliography
Parmar, Abhiraj, Roshni Sadaria, and Ronak Shah. "Diabetic Ketoacidosis Unveiling Hypertriglyceridemia-Induced Acute Pancreatitis With Concurrent Bacteraemia In A Young Adult: A Complex Multi-System Presentation." International Journal of Creative Research Thoughts 14, no. 5 (2026): b277-b282. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2605165.
Harvard — author–date
Parmar, A., Sadaria, R. and Shah, R. (2026) 'Diabetic Ketoacidosis Unveiling Hypertriglyceridemia-Induced Acute Pancreatitis With Concurrent Bacteraemia In A Young Adult: A Complex Multi-System Presentation', International Journal of Creative Research Thoughts, 14(5), pp. b277-b282. Available at: https://ijcrt.org/viewpaperforall.php?paper=IJCRT2605165
IEEE — numbered reference
A. Parmar, R. Sadaria and R. Shah, "Diabetic Ketoacidosis Unveiling Hypertriglyceridemia-Induced Acute Pancreatitis With Concurrent Bacteraemia In A Young Adult: A Complex Multi-System Presentation," IJCRT, vol. 14, no. 5, pp. b277-b282, May. 2026.
Vancouver — biomedical
Parmar A, Sadaria R, Shah R. Diabetic Ketoacidosis Unveiling Hypertriglyceridemia-Induced Acute Pancreatitis With Concurrent Bacteraemia In A Young Adult: A Complex Multi-System Presentation. IJCRT. 2026 May;14(5):b277-b282.
AMA — 11th edition
Parmar A, Sadaria R, Shah R. Diabetic Ketoacidosis Unveiling Hypertriglyceridemia-Induced Acute Pancreatitis With Concurrent Bacteraemia In A Young Adult: A Complex Multi-System Presentation. IJCRT. 2026;14(5):b277-b282. Accessed at https://ijcrt.org/viewpaperforall.php?paper=IJCRT2605165
BibTeX — Zotero, Mendeley, LaTeX
@article{IJCRT2605165,
author = {Abhiraj Parmar and Roshni Sadaria and Ronak Shah},
title = {Diabetic Ketoacidosis Unveiling Hypertriglyceridemia-Induced Acute Pancreatitis With Concurrent Bacteraemia In A Young Adult: A Complex Multi-System Presentation},
journal = {International Journal of Creative Research Thoughts},
volume = {14},
number = {5},
pages = {b277-b282},
year = {2026},
month = {May},
issn = {2320-2882},
url = {https://ijcrt.org/viewpaperforall.php?paper=IJCRT2605165}
}
RIS — EndNote, RefWorks
TY - JOUR
AU - Parmar, Abhiraj
AU - Sadaria, Roshni
AU - Shah, Ronak
TI - Diabetic Ketoacidosis Unveiling Hypertriglyceridemia-Induced Acute Pancreatitis With Concurrent Bacteraemia In A Young Adult: A Complex Multi-System Presentation
T2 - International Journal of Creative Research Thoughts
JA - IJCRT
VL - 14
IS - 5
PY - 2026
SN - 2320-2882
UR - https://ijcrt.org/viewpaperforall.php?paper=IJCRT2605165
SP - b277-b282
ER -
Issue
Volume 14 Issue 5,
May-2026
Pages : b277-b282
Article Information
- Pages
- b277-b282
- Published
- May 2026
- Registration ID
- IJCRT_307930
- Published Paper ID
- IJCRT2605165
- Research Area
- Humanities All
- Author Type
- Indian Author
- Location
- vadodara, Gujarat, India
- Peer Review
- Request Peer Review Report
- Licence
- CC BY 4.0 · Open Access
- ISSN & Impact Factor
- 2320-2882 · IF 9.17
- Downloads
- 161
- Permanent Link
- https://ijcrt.org/viewpaperforall.php?paper=IJCRT2605165
- Published Paper PDF
- https://ijcrt.org/papers/IJCRT2605165.pdf
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