ISSN2320-2882
Impact Factor9.17
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CrossRefDOI
ESTD2013
Peer ReviewTransparent
AccessOpen
Submission: Always Open
Paper Title
System Design and Pre-Analysis of TP53 Mutation Status in Human Cancer Cells
Authors
Akash Kumar Bhagat , Dr. Arvind Kumar Pandey
Keywords
TP53, machine learning, cancer cell lines,
Abstract
The research field utilizes cancer cell lines that originate from tumors to investigate cancerous processes and test new treatment methods. The TP53 gene functions as a crucial genetic element because it governs three fundamental cellular processes, which include cell cycle management, genomic restoration, and programmed cell death. Researchers must establish the TP53 mutation status of their samples because it directly affects their ability to obtain trustworthy experimental results. Researchers propose a machine learning technique to predict and assess TP53 mutation status within human cancer cell lines. The UMD TP53 database provides data which undergoes preprocessing to maintain both consistency and accuracy. The Logistic Regression model functions as a supervised classification system, which enables researchers to distinguish between mutant and wild-type cell lines based on their mutation characteristics. The proposed system combines all necessary components for data preprocessing and feature extraction and model training and evaluation into a unified operational process. The experimental results demonstrate how the model successfully detects mutation patterns while the existing datasets contain verification errors. The study demonstrates that cancer research needs validated mutation data to conduct reliable research while machine learning methods improve this reliability.
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IJCRT — journal style
"System Design and Pre-Analysis of TP53 Mutation Status in Human Cancer Cells", IJCRT - International Journal of Creative Research Thoughts (www.ijcrt.org), ISSN:2320-2882, Vol.14, Issue 4, page no.g730-g735, April 2026, Available :https://ijcrt.org/papers/IJCRT2604783.pdf
APA — 7th edition
Bhagat, A. K., & Pandey, A. K. (2026). System Design and Pre-Analysis of TP53 Mutation Status in Human Cancer Cells. International Journal of Creative Research Thoughts, 14(4), g730-g735. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2604783
MLA — 9th edition
Bhagat, Akash Kumar, and Arvind Kumar Pandey. "System Design and Pre-Analysis of TP53 Mutation Status in Human Cancer Cells." International Journal of Creative Research Thoughts, vol. 14, no. 4, 2026, pp. g730-g735, https://ijcrt.org/viewpaperforall.php?paper=IJCRT2604783.
Chicago — 17th, bibliography
Bhagat, Akash Kumar, and Arvind Kumar Pandey. "System Design and Pre-Analysis of TP53 Mutation Status in Human Cancer Cells." International Journal of Creative Research Thoughts 14, no. 4 (2026): g730-g735. https://ijcrt.org/viewpaperforall.php?paper=IJCRT2604783.
Harvard — author–date
Bhagat, A.K. and Pandey, A.K. (2026) 'System Design and Pre-Analysis of TP53 Mutation Status in Human Cancer Cells', International Journal of Creative Research Thoughts, 14(4), pp. g730-g735. Available at: https://ijcrt.org/viewpaperforall.php?paper=IJCRT2604783
IEEE — numbered reference
A. K. Bhagat and A. K. Pandey, "System Design and Pre-Analysis of TP53 Mutation Status in Human Cancer Cells," IJCRT, vol. 14, no. 4, pp. g730-g735, Apr. 2026.
Vancouver — biomedical
Bhagat AK, Pandey AK. System Design and Pre-Analysis of TP53 Mutation Status in Human Cancer Cells. IJCRT. 2026 Apr;14(4):g730-g735.
AMA — 11th edition
Bhagat AK, Pandey AK. System Design and Pre-Analysis of TP53 Mutation Status in Human Cancer Cells. IJCRT. 2026;14(4):g730-g735. Accessed at https://ijcrt.org/viewpaperforall.php?paper=IJCRT2604783
BibTeX — Zotero, Mendeley, LaTeX
@article{IJCRT2604783,
author = {Akash Kumar Bhagat and Arvind Kumar Pandey},
title = {System Design and Pre-Analysis of TP53 Mutation Status in Human Cancer Cells},
journal = {International Journal of Creative Research Thoughts},
volume = {14},
number = {4},
pages = {g730-g735},
year = {2026},
month = {April},
issn = {2320-2882},
url = {https://ijcrt.org/viewpaperforall.php?paper=IJCRT2604783}
}
RIS — EndNote, RefWorks
TY - JOUR
AU - Bhagat, Akash Kumar
AU - Pandey, Arvind Kumar
TI - System Design and Pre-Analysis of TP53 Mutation Status in Human Cancer Cells
T2 - International Journal of Creative Research Thoughts
JA - IJCRT
VL - 14
IS - 4
PY - 2026
SN - 2320-2882
UR - https://ijcrt.org/viewpaperforall.php?paper=IJCRT2604783
SP - g730-g735
ER -
Issue
Volume 14 Issue 4,
April-2026
Pages : g730-g735
Article Information
- Pages
- g730-g735
- Published
- April 2026
- Registration ID
- IJCRT_306039
- Published Paper ID
- IJCRT2604783
- Research Area
- Science and Technology
- Author Type
- Indian Author
- Location
- JHALDA, WEST BENGAL, India
- Peer Review
- Request Peer Review Report
- Licence
- CC BY 4.0 · Open Access
- ISSN & Impact Factor
- 2320-2882 · IF 9.17
- Downloads
- 110
- Permanent Link
- https://ijcrt.org/viewpaperforall.php?paper=IJCRT2604783
- Published Paper PDF
- https://ijcrt.org/papers/IJCRT2604783.pdf
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International Journal of Creative Research Thoughts
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